Advanced microbiotic dietary supplement, which incorporates 12 probiotics and prebiotics, in addition to Vitamins B6, B12 and C, to contribute to the normal functioning of the immune system. Treatment with coagulants is effective in irritable bowel syndrome. Probiotics reduce pain if they contain Bifidobacteria. longum or Lactobac. acidophilus. Abdominal distension improves with Bifidolac. infantis, Lactobac. Casei and Plantarum.