Wrist and thumb orthosis is primarily used to allow the user to maintain wrist functionality and handgrip strength in cases of "twisted thumb" or pain, metacarpophalangeal injury, sprain or rhizarthrosis. This static orthosis is made entirely of a thermomodular polymeric material. Fully covered with fabric, the orthosis is also equipped with a hook-and-loop fastening strap. Thanks to its thermoformable component, it adapts perfectly to the morphology of the user.