Argireline anti-wrinkle serum with active ingredients to reduce the depth of wrinkles caused by the contraction of the muscles of expression. It contains Argireline which is a hexapeptide of natural origin that acts as a substitute for topical use to the Butolinic Toxin A (BoNT/A), for the reduction of the depth of wrinkles caused by the contraction of the muscles of expression. Technically, Argireline is a sequence that acts on the synapse between the muscle and the neurotransmitter. When destabilized, the connection is not efficient and consequently the muscle contraction is attenuated, preventing the formation of wrinkles.