Ultramicronized palmitoylethanolamide provides properties that act in the body as a biological modulator and is able to promote at different levels the control of the physiological reactivity of the nervous tissue. In this way, it helps to control inflammatory pain and/or neuropathic pain. It favours the control of sensory endings, endoneural compartment, spinal synaptic connection between 1st and 2nd order neurons.