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Syntholkiné Multi-Zone Flexible Patches 4 Units are self-heating patches optimized for cervical, shoulder, wrist and lumbar vertebrae, providing up to 8 hours of constant heat. The heat helps to improve muscle elasticity, providing a feeling of well-being. Simply remove the patch from its packaging and place it in contact with the air, triggering a chemical reaction that generates heat that lasts 8 hours.recommended in cases of muscle pain, sciatica, lumbago, contractures, cramps or muscle pain caused by rheumatism.medical device with CE marking 0476.box of 4 patches.